Efficacy of five commercial disinfectants and one anionic surfactant against equine herpesvirus type 1

J Vet Med Sci. 2015 Nov;77(11):1545-8. doi: 10.1292/jvms.15-0030. Epub 2015 Jun 14.


We investigated the influences of various reaction conditions on equine herpesvirus type 1 (EHV-1) disinfection by 5 commercial disinfectants (3 quaternary ammonium compounds [QACs] and 2 chlorine-based disinfectants) and 1 anionic surfactant. QACs at their highest recommended concentrations had no virucidal effect on EHV-1 with a 10-min reaction time at 0°C or a 1-min reaction time at room temperature. Chlorine-based disinfectants achieved EHV-1 disinfection with a 10-min reaction time at -10°C or a 30-sec reaction time at room temperature. In the presence of 5% fetal bovine serum, QACs (except for benzalkonium chloride) showed more stable virucidal effects than did chlorine-based disinfectants. The virucidal effect of the anionic surfactant was almost equivalent to that of the QACs.

MeSH terms

  • Alkanesulfonic Acids / chemistry
  • Alkanesulfonic Acids / pharmacology*
  • Animals
  • Chlorine
  • Disinfectants / chemistry
  • Disinfectants / pharmacology*
  • Herpesvirus 1, Equid / drug effects*
  • Surface-Active Agents / chemistry
  • Surface-Active Agents / pharmacology*
  • Time Factors


  • Alkanesulfonic Acids
  • Disinfectants
  • Surface-Active Agents
  • alkylbenzyl sulfonic acid
  • Chlorine