Association of Magnesium Intake with High Blood Pressure in Korean Adults: Korea National Health and Nutrition Examination Survey 2007-2009

PLoS One. 2015 Jun 15;10(6):e0130405. doi: 10.1371/journal.pone.0130405. eCollection 2015.

Abstract

Background: Magnesium is known to lower the risk of cardiovascular disease. However, studies on its relationship with hypertension, a single and common cause of various chronic diseases, are limited and their findings are not consistent. The purpose of the present study is to identify the relationship between magnesium intake and high blood pressure (HBP) risk in Koreans.

Methods: This research is a cross-sectional study based on the 2007~2009 Korean National Health and Nutritional Examination Survey data. This study investigated 11,685 adults aged over 20 to examine their general characteristics, anthropometry and blood pressure. Daily magnesium intake was analyzed using the 24-hour dietary recall method. To calculate the odds ratio (OR) of HBP risk (130/85 mmHg or over) according to the quartile of magnesium intake (mg/1000 kcal) together with its 95% confidence interval (CI), multivariable logistic regression analysis was performed.

Results: No significant association between dietary magnesium intake and the risk of HBP was found. In obese women, particularly, after adjusting relevant factors, the adjusted odds ratio of HBP prevalence in the highest magnesium intake quartile was 0.40 compared with the lowest magnesium intake quartile (95% CI = 0.25~0.63, P for trend = 0.0014). Women, especially obese women, were found to have a negative relationship of magnesium intake with HBP.

Conclusions: The present results indicate that sufficient magnesium intake could be useful in decreasing the high blood pressure risk of obese women.

MeSH terms

  • Adult
  • Blood Pressure
  • Cross-Sectional Studies
  • Diet
  • Female
  • Humans
  • Hypertension / chemically induced*
  • Hypertension / epidemiology*
  • Magnesium / pharmacology*
  • Male
  • Nutrition Surveys
  • Obesity / metabolism*
  • Republic of Korea / epidemiology

Substances

  • Magnesium

Grant support

The authors received no specific funding for this work.