A case series of 20 women with hidradenitis suppurativa treated with spironolactone

Australas J Dermatol. 2015 Aug;56(3):192-6. doi: 10.1111/ajd.12362. Epub 2015 Jun 16.

Abstract

Hidradenitis suppurativa (HS) is an uncommon chronic skin condition that can range in severity from a single nodule to extensive disease and can have a profound effect on quality of life. Anti-androgen medication has been suggested as a possible management strategy in female patients with HS and is mentioned in review articles as a treatment option. Despite this, there is limited literature documenting the use of anti-androgens in HS. We present our experience with 20 patients with HS treated with oral spironolactone. We advocate spironolactone as a useful, low-cost first-line treatment for women with HS, with relatively few side-effects.

Keywords: anti-androgen; hidradenitis suppurativa; spironolactone.

MeSH terms

  • Adolescent
  • Adult
  • Androgen Antagonists / therapeutic use*
  • Female
  • Hidradenitis Suppurativa / drug therapy*
  • Humans
  • Middle Aged
  • Retrospective Studies
  • Spironolactone / therapeutic use*
  • Young Adult

Substances

  • Androgen Antagonists
  • Spironolactone