Case Reports
doi: 10.1093/cid/civ474.
Epub 2015 Jun 16.
Hepatitis B Virus Reactivation During Successful Treatment of Hepatitis C Virus With Sofosbuvir and Simeprevir
Affiliations
- PMID: 26082511
- DOI: 10.1093/cid/civ474
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Case Reports
Hepatitis B Virus Reactivation During Successful Treatment of Hepatitis C Virus With Sofosbuvir and Simeprevir
Clin Infect Dis.
.
Abstract
Treatment of hepatitis C virus with potent, interferon-free, direct-acting antiviral regimens with no activity against hepatitis B virus (HBV) may increase the risk for HBV reactivation in coinfected patients. We present 2 cases of HBV reactivation during treatment with an all-oral regimen of simeprevir and sofosbuvir and discuss strategies to prevent HBV flare.
Keywords: HBV reactivation; HBV/HCV coinfection; acute hepatitis; simeprevir; sofosbuvir.
© The Author 2015. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.
Comment in
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Editorial Commentary: Another Call to Cure Hepatitis B.Clin Infect Dis. 2015 Oct 15;61(8):1307-9. doi: 10.1093/cid/civ475. Epub 2015 Jun 16. Clin Infect Dis. 2015. PMID: 26082512 Free PMC article. No abstract available.
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