Gastric-type adenocarcinoma of the cervix in a patient with Lynch syndrome: A case report

M Moat; R L O'Donnell; W G McCluggage; A Ralte; R J Edmondson

doi:10.1016/j.gynor.2014.03.002

Gastric-type adenocarcinoma of the cervix in a patient with Lynch syndrome: A case report

Gynecol Oncol Rep. 2014 Mar 13:10:41-3. doi: 10.1016/j.gynor.2014.03.002. eCollection 2014 Dec.

Authors

M Moat¹, R L O'Donnell², W G McCluggage³, A Ralte⁴, R J Edmondson⁵

Affiliations

¹ Northern Institute for Cancer Research, Newcastle University Medical School, Newcastle Upon Tyne NE2 4HH, UK.
² Northern Institute for Cancer Research, Newcastle University Medical School, Newcastle Upon Tyne NE2 4HH, UK ; Northern Gynaecological Oncology Centre, Queen Elizabeth Hospital, Gateshead NE6 9SX, UK.
³ Department of Pathology, Royal Group of Hospitals Trust, Grosvenor Road, Belfast BT12 6BL, UK.
⁴ Department of Pathology, Queen Elizabeth Hospital, Gateshead NE6 9SX, UK.
⁵ University of Manchester, St Mary's Hospital, Oxford Road, Manchester, UK.

Abstract

•Lynch syndrome (LS) is an uncommon, genetic disorder which predisposes affected individuals to colorectal, endometrial and ovarian malignancies.•We report a case of cervical gastric-type adenocarcinoma in a patient with LS.•Immunohistochemistry for mismatch repair proteins is a useful screening tool in tumours suspected to be associated with LS.

Keywords: Cervical gastric-type adenocarcinoma; Lynch syndrome; MSH6.