Gingival crevicular blood as a source to screen for diabetes control in a dental office setting

Am J Dent. 2015 Apr;28(2):63-7.

Abstract

screen for diabetes control, this study compared glycosylated hemoglobin (HbAlc) levels found in GCB and serum. Methods: Patients diagnosed (n= 29), with diabetes received a venipuncture on the finger and serum blood (METHODS) obtained was tested for HbAlc status chair-side. GCB (test) was collected at site(s) with evidence of bleeding after probing and the HbAlc value was determined in the same manner as with the serum blood. Results: There was a significant correlation between serum blood and GCB using the HbAlc test. The Pearson

Results: tion was 0.98 (P< 0.0001). The Altman-Bland bias was -0.21 (P= 0.0095), indicating that on average, the GCB method slightly underestimated the venipuncture serum (control) method for determining HbA1c values. The Altman-Bland 95% agreement interval ranged from -1.02 to 0.6. Furthermore, the HbAlc values were independent of the gingival sites used for collection with intra-patient GCB values exhibiting a correlation value between sites of 0.91 (P< 0.0001).

Publication types

  • Comparative Study
  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Dental Offices*
  • Diabetes Mellitus / blood
  • Diabetes Mellitus / prevention & control*
  • Diabetes Mellitus, Type 1 / blood
  • Diabetes Mellitus, Type 1 / prevention & control
  • Diabetes Mellitus, Type 2 / blood
  • Diabetes Mellitus, Type 2 / prevention & control
  • Gingival Crevicular Fluid / chemistry*
  • Gingival Hemorrhage / blood*
  • Glycated Hemoglobin / analysis*
  • Humans
  • Mass Screening*
  • Phlebotomy
  • Point-of-Care Systems
  • Reagent Kits, Diagnostic

Substances

  • Glycated Hemoglobin A
  • Reagent Kits, Diagnostic