Factors influencing 1-year rotational stability of AcrySof Toric intraocular lenses

Br J Ophthalmol. 2016 Feb;100(2):263-8. doi: 10.1136/bjophthalmol-2015-306656. Epub 2015 Jun 18.


Purpose: To investigate the 1-year rotational stability of AcrySof Toric intraocular lenses (IOLs) and factors influencing their stability.

Methods: This retrospective study enrolled 75 patients who underwent phacoemulsification, and were implanted with an AcrySof Toric IOL for 1 year. Their preoperative clinical data were reviewed. The 1-year clinical outcomes included uncorrected visual acuity, best-corrected visual acuity and residual astigmatism. Rotation of the IOL and the grade of anterior capsular opacification (ACO; graded from 0=none to 3=severe) were evaluated after mydriasis.

Results: Of the 75 eyes analysed, 29.33% had high myopia. Residual astigmatism at 1 year (-0.76±0.47 dioptre(D)) was significantly reduced compared with the preoperative corneal astigmatism (2.08±0.71 D). The mean absolute rotation of the IOL was 8.83±5.26°. Toric IOL rotation was significantly and positively correlated with the degree of residual astigmatism in the T3 (Pearson's r=0.552, p<0.001) and T4 groups (Pearson's r=0.622, p=0.003). Regarding factors associated with IOL rotation, toric IOL rotation was positively correlated with axial length (AXL; Pearson's r=0.335, p=0.003) and negatively correlated with ACO grade (Spearman's r=-0.541, p<0.001). On multiple linear regression analysis, only AXL (B=0.889, p=0.031) and ACO grade (B=-3.216, p<0.001) were predictors of toric IOL rotation (R(2)=0.397).

Conclusions: Long AXL is a risk factor for toric IOL rotation, while higher ACO grade may decrease toric IOL rotation, indicating that reducing the polishing of anterior capsule may improve the rotational stability of a toric IOL.

Trial registration number: NCT02182921.

Keywords: Lens and zonules; Vision.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Artificial Lens Implant Migration / diagnosis
  • Artificial Lens Implant Migration / etiology
  • Artificial Lens Implant Migration / physiopathology*
  • Astigmatism / physiopathology
  • Axial Length, Eye / physiopathology
  • Capsule Opacification / physiopathology
  • Female
  • Humans
  • Lens Implantation, Intraocular*
  • Lenses, Intraocular*
  • Male
  • Middle Aged
  • Phacoemulsification*
  • Retrospective Studies
  • Risk Factors
  • Rotation*
  • Visual Acuity / physiology

Associated data

  • ClinicalTrials.gov/NCT02182921