Nanomaterials and Optical Diagnosis of HIV

Artif Cells Nanomed Biotechnol. 2016 Sep;44(6):1383-90. doi: 10.3109/21691401.2015.1052469. Epub 2015 Jun 23.


The investigators had previously shown that the risk of AIDS/HIV-related illness and transmission reduced (by 96%) with early antiretroviral treatment. Nanomaterials could be applied in early diagnosis of HIV by improving the ability to detect serum biomarkers of the blood-borne infectious diseases, with low sample volume, rapidity, and more sensitivity than currently available FDA-approved methods such as ELISA, particle agglutination assay, and Western Blotting assay. We have demonstrated several experimental studies for optical HIV diagnosis based on nanomaterials in three categories (e.g., the fluorescence-, the SPR-, and the SERS- based biosensors), and have explained each assay.

Keywords: Diagnosis; HIV; Nanomaterials; Nanotechnology.

Publication types

  • Review

MeSH terms

  • Acquired Immunodeficiency Syndrome / diagnosis*
  • Acquired Immunodeficiency Syndrome / genetics
  • Biosensing Techniques / methods*
  • HIV*
  • Humans
  • Nanostructures / chemistry*
  • Optogenetics / methods*