Pancreatic mucinous cystic neoplasm in a transgender patient

World J Surg Oncol. 2015 Jun 24;13:205. doi: 10.1186/s12957-015-0620-8.

Abstract

Background: Cystic pancreatic lesions are increasingly more frequent detected clinical entities. Mucinous cystic neoplasm (MCN) is a hormone-related pancreatic tumor (HRTP) with a strong predominance in young and middle-aged females.

Case presentation: Here, we present the case of a 31-year-old surgically transgendered female-to-male patient with a history of alcoholic pancreatitis, on chronic testosterone therapy. He was found to have a pancreatic MCN and underwent distal pancreatectomy and splenectomy.

Conclusion: To our knowledge, this is the first reported case of a transgender patient with a history of hormone replacement therapy (HRT) and pancreatic MCN. We consider possible mechanisms for the pathogenesis to explain this patient's neoplasm.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Cystadenoma, Mucinous / pathology*
  • Cystadenoma, Mucinous / surgery
  • Female
  • Humans
  • Male
  • Pancreatectomy
  • Pancreatic Neoplasms / pathology*
  • Pancreatic Neoplasms / surgery
  • Prognosis
  • Transgender Persons*