[Neuropsychological deficits in alternating hemiplegia of childhood: a case study]

Rev Neurol. 2015 Jul 1;61(1):25-8.
[Article in Spanish]

Abstract
in En , Spanish

Introduction: Alternating hemiplegic of childhood is a predominantly sporadic neurodevelopmental syndrome of uncertain etiology, characterized by alternating transient attacks of hemiplegia. Additional features include tonic fits, dystonic posturing, ocular motor abnormalities and deficits in cognitive functioning.

Case report: A girl of 7 years-old with alternating hemiplegic of childhood. The first symptoms debut at 17 months of age in the form of lower limb weakness, migraine, nystagmus and hemiplegic crisis alternating both hemibodies. We administrate the Wechsler Intelligence Scale for Children IV (WISC-IV), the Conners Continuous Performance Test II (CPT-II), the Conners scales for parents (CPRS-48) and teachers (CTRS-28) and the Behavior Rating Inventory Executive Function (BRIEF).

Conclusions: In our study we found deficits in sustained attention, reduced speed of information processing, and difficulties in understanding, speaking and working memory. In addition, parents and teachers reported behavioral disturbances, difficulties inhibition capability, in self-control and in regulating emotions.

Title: Deficits neuropsicologicos en la hemiplejia alternante infantil: estudio de un caso.

Introduccion. La hemiplejia alternante infantil es un sindrome del neurodesarrollo de etiologia incierta, caracterizado por la presencia de ataques transitorios de hemiplejia. Las caracteristicas adicionales incluyen crisis epilepticas, distonia, anomalias motoras oculares y deficits en el funcionamiento cognitivo. Caso clinico. Niña de 7 años con hemiplejia alternante infantil. Los primeros sintomas comenzaron a los 17 meses en forma de debilidad en los miembros inferiores, migrañas, nistagmo y crisis hemiplejicas que alternaban ambos hemicuerpos. Se administro la escala de inteligencia de Wechsler para niños IV (WISC-IV) y el Conners Continuous Performance Test II (CPT-II), asi como las escalas de Conners para padres (CPRS-48) y profesores (CTRS-28) y el Behavior Rating Inventory Executive Function (BRIEF). Conclusiones. En nuestro estudio encontramos deficits en atencion sostenida, reduccion de la velocidad de procesamiento de la informacion, y dificultades en la comprension, expresion verbal y memoria de trabajo. Ademas, los padres y profesores comunicaron conductas problematicas, y dificultades en la capacidad de inhibicion, en el autocontrol y en la regulacion de emociones.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Attention
  • Child
  • Child Behavior Disorders / etiology
  • Comprehension
  • Emotions
  • Female
  • Flunarizine / therapeutic use
  • Hemiplegia / diagnosis
  • Hemiplegia / drug therapy
  • Hemiplegia / psychology*
  • Humans
  • Memory Disorders / etiology
  • Memory, Short-Term
  • Mental Processes
  • Neuroimaging
  • Neurologic Examination
  • Neuropsychological Tests
  • Psychomotor Performance
  • Severity of Illness Index
  • Speech Disorders / etiology

Substances

  • Flunarizine

Supplementary concepts

  • Alternating hemiplegia of childhood