Psychopharmacologic treatment of dissociative fugue and PTSD in an Ethiopian refugee

J Clin Psychiatry. 2015 Jul;76(7):958. doi: 10.4088/JCP.14cr09334.

Abstract

Despite widespread awareness of their frequent co-occurrence, little is known about treatment of individuals with comorbid posttraumatic stress disorder (PTSD) and dissociative disorders. Patients with dissociative disorders do not respond well to standard exposure therapy, and few psychopharmacologic trials exist. Fluoxetine proved ineffective for depersonalization disorder, but paroxetine showed efficacy in decreasing dissociative symptoms in PTSD patients.

Publication types

  • Case Reports

MeSH terms

  • Adrenergic alpha-1 Receptor Antagonists / administration & dosage
  • Adrenergic alpha-1 Receptor Antagonists / pharmacology*
  • Comorbidity
  • Dissociative Disorders / diagnosis
  • Dissociative Disorders / drug therapy*
  • Ethiopia
  • Humans
  • Male
  • Middle Aged
  • Prazosin / administration & dosage
  • Prazosin / pharmacology
  • Refugees / psychology
  • Selective Serotonin Reuptake Inhibitors / administration & dosage
  • Selective Serotonin Reuptake Inhibitors / pharmacology*
  • Sertraline / administration & dosage
  • Sertraline / pharmacology
  • Stress Disorders, Post-Traumatic / diagnosis
  • Stress Disorders, Post-Traumatic / drug therapy*
  • Treatment Outcome
  • United States

Substances

  • Adrenergic alpha-1 Receptor Antagonists
  • Serotonin Uptake Inhibitors
  • Sertraline
  • Prazosin