Regenerative Approach to Velopharyngeal Incompetence with Fat Grafting

Clin Plast Surg. 2015 Jul;42(3):365-74, ix. doi: 10.1016/j.cps.2015.03.002. Epub 2015 Apr 28.

Abstract

Surgical management of velopharyngeal incompetence (VPI) aims at improving voice resonance and correcting nasal air escape by restoring a competent velopharyngeal sphincter. Assessment of VPI requires the examination of multiple variables. The dynamic study of movements of the velopharyngeal port during speech and the quantification of the closure gap, using flexible videonasoendoscopy and/or videofluoroscopy, is essential. Autologous fat injection represents a minimally invasive alternative to major surgery in the management of mild to moderate VPI that minimizes the risk of complications and sequelae, and can be performed without modifying the anatomy of the velopharyngeal port.

Keywords: Fat grafting; Hypernasality; Nasal air escape; Nasoendoscopy; Regenerative medicine; Submucous cleft; Velopharyngeal incompetence.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adipose Tissue / transplantation*
  • Adolescent
  • Child
  • Endoscopy
  • Humans
  • Plastic Surgery Procedures
  • Regeneration
  • Tissue Transplantation
  • Tissue and Organ Harvesting
  • Transplantation, Autologous
  • Velopharyngeal Insufficiency / physiopathology
  • Velopharyngeal Insufficiency / surgery*