Intra-operative digital specimen radiology reduces re-operation rates in therapeutic mammaplasty for breast cancer

Breast. 2015 Oct;24(5):556-9. doi: 10.1016/j.breast.2015.04.007. Epub 2015 Jun 26.

Abstract

Background: The aim of this study was to evaluate our experience with intra-operative imaging of therapeutic mammaplasty specimens at Edinburgh Breast Unit.

Methods: A retrospective review was performed of patients who underwent therapeutic mammaplasty in Edinburgh Breast Unit between 2007 and 2013 who had intraoperative specimen radiography.

Results: 98 (100%) patients who underwent therapeutic mammaplasty for breast cancer had intra-operative imaging using the faxitron(®) system. 3 out of those 97 (3%) patients had a re-operation because of positive margins confirmed pathologically on cavity excision specimens, but only 1 out of 3 (1%) patients had residual breast cancer present within the re-excision specimen. None required mastectomy. Median age was 58 (range 34-81). Median follow up was 3.1 years (range 6 months - 5.5 years). There was no local recurrence or conversion to mastectomy in this group.

Conclusion: Complete excision rate in patients who had intra-operative imaging during therapeutic mammaplsty procedure was 97% in our group. Faxitron(®) system is a useful adjunct in helping to achieve low incomplete excision rates.

Keywords: Breast cancer; Breast conserving surgery; Breast reconstruction; Therapeutic mammaplasty.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Antineoplastic Agents, Hormonal / therapeutic use
  • Breast Neoplasms / diagnostic imaging*
  • Breast Neoplasms / pathology
  • Breast Neoplasms / surgery
  • Carcinoma, Ductal, Breast / diagnostic imaging*
  • Carcinoma, Ductal, Breast / pathology
  • Carcinoma, Ductal, Breast / surgery
  • Carcinoma, Intraductal, Noninfiltrating / diagnostic imaging*
  • Carcinoma, Intraductal, Noninfiltrating / pathology
  • Carcinoma, Intraductal, Noninfiltrating / surgery
  • Carcinoma, Lobular / diagnostic imaging*
  • Carcinoma, Lobular / pathology
  • Carcinoma, Lobular / surgery
  • Chemotherapy, Adjuvant
  • Female
  • Follow-Up Studies
  • Humans
  • Intraoperative Care
  • Mammaplasty
  • Mammography*
  • Mastectomy, Segmental / methods*
  • Middle Aged
  • Neoadjuvant Therapy
  • Neoplasm, Residual
  • Reoperation / statistics & numerical data
  • Retrospective Studies

Substances

  • Antineoplastic Agents, Hormonal