8-methoxypsoralen plus UVA (PUVA) therapy normalizes signalling of phosphorylated component of mTOR pathway in psoriatic skin of K5.hTGFβ1 transgenic mice

Exp Dermatol. 2015 Nov;24(11):889-91. doi: 10.1111/exd.12779. Epub 2015 Sep 15.

Authors

Nitesh Shirsath^{1

2}, Gerlinde Mayer², Tej Pratap Singh^{1

2}, Peter Wolf²

Affiliations

¹ Center for Medical Research, Medical University of Graz, Graz, Austria.
² Research Unit for Photodermatology, Department of Dermatology and Venereology, Medical University of Graz, Graz, Austria.

PMID: 26121067
DOI: 10.1111/exd.12779

No abstract available

Keywords: PUVA; mammalian target of rapamycin (mTOR); psoralen; psoriasis; transgenic mouse model.

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Animals
Mice, Transgenic
PUVA Therapy*
Phosphorylation
Psoriasis / metabolism
Psoriasis / therapy*
Ribosomal Protein S6 / metabolism*
TOR Serine-Threonine Kinases / metabolism*

Substances

Ribosomal Protein S6
mTOR protein, mouse
TOR Serine-Threonine Kinases