Recurrent acute proptosis in atypical systemic lupus erythematosus

Clin Rheumatol. 1989 Dec;8(4):528-32. doi: 10.1007/BF02032109.


A patient is described who developed acute proptosis, a rare complication of systemic lupus erythematosus, 16 years after the onset of the disease. Treatment with intravenous methylprednisolone produced rapid improvement, but swelling recurred a few days later. Intravenous corticosteroid was again effective and was continued orally without further episodes of proptosis. This patient is unusual in the long period of mild disease before the development of systemic complications, and in having antibodies to nuclear ribonucleoprotein but persistently normal titres of DNA-binding antibodies in her serum.

Publication types

  • Case Reports

MeSH terms

  • Acute Disease
  • Adult
  • Exophthalmos / diagnostic imaging
  • Exophthalmos / drug therapy
  • Exophthalmos / etiology*
  • Female
  • Humans
  • Lupus Erythematosus, Systemic / complications*
  • Methylprednisolone / therapeutic use
  • Recurrence
  • Tomography, X-Ray Computed


  • Methylprednisolone