Time From Infection to Disease and Infectiousness for Ebola Virus Disease, a Systematic Review

Clin Infect Dis. 2015 Oct 1;61(7):1135-40. doi: 10.1093/cid/civ531. Epub 2015 Jun 30.


We systematically reviewed the literature to estimate the incubation and latent periods of Ebola virus disease. We found limited epidemiological data from individuals with discrete 1-day exposures. Available data suggest that the incubation and latent periods may differ, and mathematical models may be improved by distinguishing between the two periods.

Keywords: Ebola; incubation period; latent period; systematic review; transmission.

Publication types

  • Research Support, N.I.H., Extramural
  • Review
  • Systematic Review

MeSH terms

  • Ebolavirus*
  • Hemorrhagic Fever, Ebola* / epidemiology
  • Hemorrhagic Fever, Ebola* / transmission
  • Hemorrhagic Fever, Ebola* / virology
  • Humans
  • Infectious Disease Incubation Period*
  • Time Factors
  • Virus Latency