Diaphragmatic muscle fibre necrosis in SIDS

Forensic Sci Int. 1989 Dec;43(3):281-91. doi: 10.1016/0379-0738(89)90156-4.


Observations of acute muscle fibre necrosis, as seen in 242 sudden infant death syndrome (SIDS) cases is described. The lesion is a focal acute anoxic muscle fibre coagulative necrosis in some cases followed by myocytolysis, central vacuolation, macrophage and phagocytic cell infiltrate, stromal condensation and scarring.

MeSH terms

  • Diaphragm / pathology*
  • Humans
  • Infant
  • Necrosis
  • Sudden Infant Death / pathology*