Copper, magnesium, zinc and calcium status in osteopenic and osteoporotic post-menopausal women

Clin Cases Miner Bone Metab. Jan-Apr 2015;12(1):18-21. doi: 10.11138/ccmbm/2015.12.1.018.


Copper, magnesium, zinc and calcium status were measured in postmenopausal women with osteoporosis (n = 23) and osteopenia (n = 28) as classified on the basis of the T-score of the femur neck and dual energy X-ray absorptiometry results. Anthropometric indices, dietary intake and serum copper, magnesium, zinc and calcium were assessed. The results of our study showed that the mean dietary intake of magnesium, zinc and calcium in post-menopausal women with low bone density were significantly lower than recommended dietary allowance. The mean serum levels of zinc (P = 0.001) and copper (P = 0.000) were significantly lower than normal range and 40.4% of this participants had serum magnesium levels lower than normal range. No statistically significant differences were observed between the osteopenic and osteoporotic groups with respect to serum levels and dietary intakes of copper, calcium, magnesium and zinc. Due to the mineral deficiency in post-menopausal women with low bone density and the key role of minerals on bone health, supplementation with magnesium, calcium, zinc and perhaps copper recommended.

Keywords: calcium; copper; magnesium; osteopenia; osteoporosis; zinc.

Publication types

  • Review