Abstract
The known styrylpyrone, goniotriol, has been isolated from Goniothalamus giganteus. Its bioactivities are reported, and its structure and relative stereochemistry have been determined by X-ray crystallography as 6R-(7R,8R-dihydro-7,8-dihydroxystyryl)-5S,6R-dihydro-5-hydroxy-2-p yrone.
Publication types
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Animals
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Antineoplastic Agents, Phytogenic / isolation & purification
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Artemia / drug effects
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Crystallography
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Drug Screening Assays, Antitumor
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Humans
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Molecular Structure
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Plants / analysis*
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Pyrans / isolation & purification*
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Pyrones / isolation & purification*
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Pyrones / pharmacology
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Tumor Cells, Cultured
Substances
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Antineoplastic Agents, Phytogenic
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Pyrans
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Pyrones
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goniotriol