MRI study of Baló's concentric sclerosis before and after immunosuppressive therapy

J Neurol. 1989 Dec;236(8):487-8. doi: 10.1007/BF00328514.


An intra vitam diagnosis of Baló's concentric sclerosis in a 39-year-old male is described. To our knowledge this is the first reported case of ante-mortem diagnosis based solely on magnetic resonance imaging (MRI) findings. MRI showed features unique to this process. After high-dose intravenous therapy with prednisone, the clinical symptoms improved, and MRI showed marked changes of the concentric lesions.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Brain Diseases / diagnosis*
  • Brain Diseases / therapy
  • Humans
  • Immunosuppression Therapy
  • Magnetic Resonance Imaging*
  • Male
  • Prednisone / therapeutic use*
  • Sclerosis / diagnosis*
  • Sclerosis / therapy


  • Prednisone