Abstract
We report a flexible de novo synthesis of phenolic dihydroxanthene fluorophores. The synthesis relies on a one-pot formation of an aldehyde intermediate which can be diversified in 60-70% overall yield, providing an efficient access to this family of near-infrared emitting fluorophores.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Fluorescent Dyes / chemical synthesis*
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Fluorescent Dyes / chemistry
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Phenols / chemical synthesis*
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Phenols / chemistry
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Spectroscopy, Near-Infrared*
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Xanthenes / chemical synthesis*
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Xanthenes / chemistry
Substances
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Fluorescent Dyes
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Phenols
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Xanthenes