We compared the incidence of angiographic cystoid macular edema (CME) in eyes with ultraviolet (UV)-absorbing intraocular lenses (IOLs) with that in eyes with non-UV-absorbing IOLs. Fifty-five bilateral pseudophakic patients received a UV-absorbing IOL in one eye and a non-UV-absorbing IOL in the fellow eye. All cases were implanted with posterior chamber lenses following extracapsular cataract extraction. Fluorescein angiography for CME was performed at least six months postoperatively (average 20.0 months). There was no statistically significant difference in visual acuity or in the incidence of CME.