High Amylose White Rice Reduces Post-Prandial Glycemic Response but Not Appetite in Humans

Nutrients. 2015 Jul 2;7(7):5362-74. doi: 10.3390/nu7075225.


The present study compared the effects of three rice cultivars on postprandial glycemic control and appetite. A single-blind, randomized, crossover clinical trial was performed with 18 healthy subjects, nine males and nine females. Three treatments were administered at three separate study visits: commercially available conventional white rice (short grain), specialty high amylose white rice 1 (Dixiebelle), and specialty high amylose white rice 2 (Rondo). Postprandial capillary blood glucose, venous blood glucose and insulin measurements, and appetite visual analog scale (VAS) surveys were done over the course of two hours. The capillary blood glucose concentrations were significantly lower for Rondo compared to short grain rice at 30 min, and for Dixiebelle and Rondo compared to short grain rice at 45, 60, and 120 min. Capillary blood glucose area under the curve (AUC) was significantly lower for Dixiebelle and Rondo compared to short grain rice. Subjects were significantly more hungry at 30 min after Dixiebelle intake than Rondo intake, but there were no other significant effects in appetite ratings. The present study determined that intake of high amylose rice with resistant starch (RS) can attenuate postprandial blood glucose and insulin response in comparison to short grain rice.

Keywords: appetite; dietary fiber; glucose; high amylose; insulin; short grain rice; visual analog scale.

Publication types

  • Randomized Controlled Trial
  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Adult
  • Amylose / administration & dosage*
  • Amylose / metabolism
  • Appetite / physiology*
  • Area Under Curve
  • Blood Glucose / analysis
  • Blood Glucose / metabolism*
  • Cross-Over Studies
  • Female
  • Healthy Volunteers
  • Humans
  • Hunger / physiology
  • Insulin / blood
  • Male
  • Oryza / chemistry
  • Oryza / metabolism*
  • Postprandial Period / physiology*
  • Satiation / physiology
  • Single-Blind Method
  • Visual Analog Scale
  • Young Adult


  • Blood Glucose
  • Insulin
  • Amylose