Possible adverse effects of frying with vegetable oils

Br J Nutr. 2015 Apr;113 Suppl 2:S49-57. doi: 10.1017/S0007114514002347.


The question of whether heated fats in the diet may be detrimental to health is nowadays of the upmost concern, but finding an answer is not easy and requires careful consideration of different aspects of lipid oxidation. This review is divided into two sections. The first part deals with the nature of the new compounds formed at high temperature in the frying process as well as their occurrence in the diet while the second part focuses on their possible nutritional and physiological effects. Oxidation products present in abused frying fats and oils are the compounds most suspected of impairing the nutritional properties of the oils or involving adverse physiological effects. The recent studies on their health implications include those related to their fate and those focused on their effects in metabolic pathways and the most prevalent diseases.

Keywords: Frying; Oxidation products; Oxidised triacylglycerols; Triacylglycerol polymers; Vegetable oils.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Cooking*
  • Diet, High-Fat / adverse effects
  • Diet, Mediterranean / adverse effects
  • Dietary Fats, Unsaturated / adverse effects*
  • Dietary Fats, Unsaturated / analysis
  • Food Contamination / prevention & control
  • Hot Temperature / adverse effects
  • Humans
  • Hydrolysis
  • Models, Chemical*
  • Nutrition Policy*
  • Oxidation-Reduction
  • Plant Oils / adverse effects*
  • Plant Oils / chemistry
  • Triglycerides / adverse effects*
  • Triglycerides / chemistry


  • Dietary Fats, Unsaturated
  • Plant Oils
  • Triglycerides