Obesity not associated with severity among hospitalized adults with seasonal influenza virus infection

Infection. 2015 Oct;43(5):569-75. doi: 10.1007/s15010-015-0802-x. Epub 2015 Jul 7.


We examined seasonal influenza severity [artificial ventilation, intensive care unit (ICU) admission, and radiographic-confirmed pneumonia] by weight category among adults hospitalized with laboratory-confirmed influenza. Using multivariate logistic regression models, we found no association between obesity or severe obesity and artificial ventilation or ICU admission; however, overweight and obese patients had decreased risk of pneumonia. Underweight was associated with pneumonia (adjusted odds ratio 1.31; 95 % confidence interval 1.04, 1.64).

Keywords: BMI; Body mass index; Influenza; Influenza hospitalizations; Obesity; Severe influenza.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Critical Care
  • Female
  • Hospitalization
  • Humans
  • Influenza, Human / complications
  • Influenza, Human / pathology*
  • Male
  • Middle Aged
  • Obesity / complications*
  • Pneumonia / pathology
  • Respiration, Artificial
  • Young Adult