Complete genome sequence of Burkholderia pyrrocinia 2327(T), the first industrial bacterium which produced antifungal antibiotic pyrrolnitrin

Yunyoung Kwak; Jae-Ho Shin

doi:10.1016/j.jbiotec.2015.06.420

Complete genome sequence of Burkholderia pyrrocinia 2327(T), the first industrial bacterium which produced antifungal antibiotic pyrrolnitrin

J Biotechnol. 2015 Oct 10:211:3-4. doi: 10.1016/j.jbiotec.2015.06.420. Epub 2015 Jul 3.

Authors

Yunyoung Kwak¹, Jae-Ho Shin²

Affiliations

¹ School of Applied Biosciences, College of Agriculture and Life Sciences, Kyungpook National University, Daegu 702-701, Republic of Korea.
² School of Applied Biosciences, College of Agriculture and Life Sciences, Kyungpook National University, Daegu 702-701, Republic of Korea. Electronic address: jhshin@knu.ac.kr.

PMID: 26150017
DOI: 10.1016/j.jbiotec.2015.06.420

Abstract

Burkholderia pyrrocinia 2327(T) (=DSM 10685(T), having an origin history as a strain Fujisawa Pharm 2327(T) from Fujisawa Pharmaceutical Co., Ltd.) is the first industrial bacterium for the isolation of antifungal antibiotic pyrrolnitrin. Herein, we present the first complete genome sequence of strain 2327(T), which consists of three circular chromosomes with one plasmid for the total 7,961,346bp sized genome with a GC content of 66.5%. This information will provide better understanding of molecular mechanisms in strain 2327(T), leading the insight of whole-cell system for the practical application of strain with the virtue of antibiotic capacity.

Keywords: Antifungal compound; Burkholderia pyrrocinia; Complete genome; Pyrrolnitrin.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Anti-Bacterial Agents / pharmacology*
Antifungal Agents / pharmacology*
Base Sequence
Burkholderia / genetics*
Genome, Bacterial*
Industrial Microbiology*
Pyrrolnitrin / pharmacology*

Substances

Anti-Bacterial Agents
Antifungal Agents
Pyrrolnitrin