Focal frontal epileptiform discharges in a patient with eyelid myoclonia and absence seizures

Epilepsy Behav Case Rep. 2015 Jun 25;4:35-7. doi: 10.1016/j.ebcr.2015.06.006. eCollection 2015.


Eyelid myoclonia with absences is classified as a unique type of generalized seizure. Its pathogenesis is proposed to involve the functional abnormalities in cortical-subcortical networks. Here, we describe the case of a 7-year-old boy who had eyelid myoclonia with absences, along with focal motor seizures. Video-EEG monitoring demonstrated eyelid myoclonia associated with 4- to 5-Hz generalized polyspike-waves preceded by focal frontal discharges. Interictal EEG showed focal epileptiform discharges over the frontal regions. Our case suggests an important role of the frontal lobe in the generation of eyelid myoclonia with absences.

Keywords: Absences; Eyelid myoclonia; Frontal lobe; Generalized seizures; Video-EEG.