Amoebic liver abscess: a report from central India

Trop Doct. 2016 Jan;46(1):12-5. doi: 10.1177/0049475515592283. Epub 2015 Jul 8.


Amoebic liver abscess is a serious but curable hepatic illness predominantly seen in tropical countries. We describe our experience of clinical presentation, laboratory parameters, radiological findings and treatment strategies. This is a retrospective analysis of 114 patients who were admitted from January 2012 to September 2014 at our centre. The mean age of presentation was 41.7 ± 13.9 years, the majority of patients were male (86.8%) with chronic alcoholism (63.2%). Most of the patients had a solitary right lobe liver abscess. Abdominal pain, fever, tachycardia and hepatomegaly were the most common clinical findings while hypoalbuminaemia, anaemia, leucocytosis and electrolyte imbalance were the most common laboratory abnormalities. A significant number of patients could be managed with antibiotics only (45.6%), percutaneous radiological drainage techniques being an important adjunct in selected cases (percutaneous needle aspiration, 20.2%; percutaneous pigtail catheter drainage, 30.7%). Surgical intervention was required in only a few cases (3.5%). Mortality was 3.5%.

Keywords: Liver abscess; amoebiasis; clinical profile.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Anti-Bacterial Agents / therapeutic use
  • Drainage
  • Entamoeba histolytica / isolation & purification
  • Female
  • Humans
  • India / epidemiology
  • Liver Abscess, Amebic / drug therapy
  • Liver Abscess, Amebic / epidemiology*
  • Liver Abscess, Amebic / surgery
  • Male
  • Middle Aged
  • Retrospective Studies
  • Young Adult


  • Anti-Bacterial Agents