Metastatic Merkel Cell Carcinoma (MCC) of Pancreas

Chirurgia (Bucur). 2015 May-Jun;110(3):287-90.


Merkel cell carcinoma (MCC) is a rare, agressive, neurocutaneous malignancy with a high potential to metastasize. We present a 59 year-old woman referred to general surgery department with a complaint of epigastric pain. The abdominal computed tomography (CT) performed and revealed amass of 3 cm in the head of the pancreas. The significant debate in the patient's medical history was that she had a MCC in size of 5 cm removed from the left gluteal region 7 months ago. Following preoperative preparation a pancreatic oduodenectomy with Whipple procedure was performed fort hepancreatic head mass. As the tumor showed morphologically similar properties with the patient's primary neoplasm, it was accepted as a metastatic MCC. Following the operation the patient received adjuvant chemotherapy and at a 30 months follow-up it was observed that the patient is disease free and has no complications related to the disease progression or recurrence. Although MCC is an aggresive and poor prognostic tumor, good results can be obtained with correct diagnosis and proper surgical treatment.

Publication types

  • Case Reports

MeSH terms

  • Carcinoma, Merkel Cell / secondary*
  • Carcinoma, Merkel Cell / therapy*
  • Chemotherapy, Adjuvant*
  • Female
  • Humans
  • Middle Aged
  • Pancreatic Neoplasms / secondary*
  • Pancreatic Neoplasms / therapy*
  • Pancreaticoduodenectomy* / methods
  • Treatment Outcome