Response to: the nature of evidence for and against epigenetic inheritance

Genome Biol. 2015 Jul 11;16(1):138. doi: 10.1186/s13059-015-0714-1.

Abstract

We thank Dr. Nadeau for his interest in our work. Dr. Nadeau has raised concerns about the experimental approach (mouse strains, route of administration, lack of phenotypic assessment) and about the validity of our conclusions. We will respond to each of these concerns point-by point.Please see related article: www.dx.doi.org/10.1186/s13059-015-0709-y.

Publication types

  • Letter
  • Comment

MeSH terms

  • Animals
  • Cellular Reprogramming / genetics*
  • DNA Methylation / genetics*
  • Epigenesis, Genetic / drug effects*
  • Female
  • Genomic Imprinting / drug effects*
  • Male
  • Pregnancy