[Cardiorenal Syndrome Type 1 in the Intensive Coronary Care Unit of the Hospital Nacional Arzobispo Loayza]

Arch Cardiol Mex. Jul-Sep 2015;85(3):176-87. doi: 10.1016/j.acmx.2015.05.004. Epub 2015 Jul 8.
[Article in Spanish]


Objectives: This study sought to evaluate the incidence of cardiorenal syndrome (CRS) type 1 in a coronary care unit and its association with hospital mortality within 30 days of admission, as well as other epidemiological characteristics.

Methods: The medical records of all the patients who were hospitalized with the diagnosis of acute heart failure in a 4-year period were reviewed. CRS type 1 was characterized by the presence of acute heart failure and an elevation of serum creatinine ≥0.3mg/dL in comparison to the baseline creatinine calculated by the MDRD75 equation and/or the elevation of ≥50% of the admission serum creatinine within a 48 h period.

Results: The incidence of CRS type 1 was 27.87%, 95% CI: 20.13-36.71 (34 of 122). There was a higher frequency of CRS type 1 in those patients who were admitted with the diagnosis of cardiogenic shock (adjusted RR 2.02, 95% CI: 1.20-3.93, p=0.0378) and in those with higher hemoglobin levels (p=0.0412). The CRS type 1 was associated with an increase of 30-day mortality (HR: 4.11, 95% CI: 1.20-14.09, p=0.0244).

Conclusions: The incidence of CRS type 1 in the coronary care unit found in our study is similar to those found in foreign studies. The history of stroke and the higher values of hemoglobin were associated with a higher incidence of cardiorenal syndrome type 1. Patients with CRS type 1 had a higher hospital mortality within 30 days of admission.

Keywords: Cardio-renal syndrome; Heart failure; Hospital mortality; Insuficiencia cardíaca; Insuficiencia renal; Mortalidad hospitalaria; Peru; Perú; Renal insufficiency; Síndrome cardiorrenal.

Publication types

  • Observational Study

MeSH terms

  • Aged
  • Cardio-Renal Syndrome / classification
  • Cardio-Renal Syndrome / epidemiology*
  • Cardio-Renal Syndrome / therapy
  • Cohort Studies
  • Coronary Care Units
  • Female
  • Hospital Mortality
  • Hospitalization
  • Humans
  • Incidence
  • Male
  • Mexico
  • Middle Aged
  • Records
  • Retrospective Studies
  • Surveys and Questionnaires