Regulating Antibiotics in an Era of Resistance: The Historical Basis and Continued Need for Adequate and Well-Controlled Investigations

Ann Intern Med. 2015 Sep 1;163(5):386-8. doi: 10.7326/M15-0802.
No abstract available

Publication types

  • Historical Article

MeSH terms

  • Anti-Bacterial Agents / therapeutic use*
  • Controlled Clinical Trials as Topic / history*
  • Drug Approval / legislation & jurisprudence*
  • Drug Resistance, Bacterial*
  • History, 20th Century
  • History, 21st Century
  • Humans
  • United States
  • United States Food and Drug Administration


  • Anti-Bacterial Agents