[The vitamin B1 and C content in the tissues of animals with thyrotoxicosis]

Vrach Delo. 1989 Oct;(10):17-8.
[Article in Russian]


The authors studied the effect of toxic doses of thyroxin on the content of vitamins C and B1 in different tissues of rats. On the 15-th day after administration of thyroxin one could observe a reduction of thiamin in the tissues of the animals. These changes were most pronounced in the liver. The content of vitamin in the tissues also showed a reduction. These changes in the content of the ascorbic acid occurred after prolonged administration of thyroxin.

Publication types

  • English Abstract

MeSH terms

  • Animals
  • Ascorbic Acid / metabolism*
  • Disease Models, Animal
  • Liver / drug effects
  • Liver / metabolism
  • Rats
  • Thiamine / metabolism*
  • Thyrotoxicosis / chemically induced
  • Thyrotoxicosis / metabolism*
  • Thyroxine / toxicity
  • Tissue Distribution


  • Ascorbic Acid
  • Thyroxine
  • Thiamine