A Rare Association of Childhood Alopecia Areata and Blepharophimosis-Ptosis-Epicanthus Inversus Syndrome: Successfully Treated with Diphenylcyclopropenone

Soumya Jagadeesan; Pradeep Balasubramanian; Vinitha Varghese Panicker; Gopikrishnan Anjaneyan; Jacob Thomas

doi:10.4103/0974-7753.160118

A Rare Association of Childhood Alopecia Areata and Blepharophimosis-Ptosis-Epicanthus Inversus Syndrome: Successfully Treated with Diphenylcyclopropenone

Int J Trichology. 2015 Apr-Jun;7(2):77-9. doi: 10.4103/0974-7753.160118.

Authors

Soumya Jagadeesan¹, Pradeep Balasubramanian², Vinitha Varghese Panicker¹, Gopikrishnan Anjaneyan¹, Jacob Thomas¹

Affiliations

¹ Department of Dermatology, Amrita Institute of Medical Sciences, Kochi, Kerala, India.
² Department of Dermatology, PSG Institute of Medical Sciences and Research, Peelamedu, Coimbatore, Tamil Nadu, India.

Abstract

The genetic background of alopecia areata has only recently begun to get unraveled. We report the association of a case of pediatric alopecia areata with a rare genetic syndrome-blepharophimosis-ptosis-epicanthus inversus syndrome (BPES), which responded well to topical immunotherapy with diphenylcyclopropenone. In the background of increasing evidence surfacing on the genetic basis of alopecia areata, this association may be of significance.

Keywords: Alopecia areata; blepharophimosis-ptosis-epicanthus inversus syndrome; contact immunotherapy; diphenylcyclopropenone; genetic basis.

Publication types

Case Reports