Loss of Vancomycin-Resistant Enterococcus Fecal Dominance in an Organ Transplant Patient With Clostridium difficile Colitis After Fecal Microbiota Transplant

Open Forum Infect Dis. 2015 Jun 3;2(2):ofv078. doi: 10.1093/ofid/ofv078. eCollection 2015 Apr.


We report the use of fecal microbiota transplantation in a single heart-kidney transplant recipient with recurrent Clostridium difficile, vancomycin-resistant Enterococcus (VRE) fecal dominance, and recurrent VRE infections. Fecal microbiota transplantation resulted in the reconstruction of a diverse microbiota with (1) reduced relative abundance of C difficile and VRE and (2) positive clinical outcome.

Keywords: C difficile; VRE; fecal microbiota transplant; gut microbiome; vancomycin-resistant Enterococcus.