BigNeuron: Large-Scale 3D Neuron Reconstruction from Optical Microscopy Images

Neuron. 2015 Jul 15;87(2):252-6. doi: 10.1016/j.neuron.2015.06.036.


Understanding the structure of single neurons is critical for understanding how they function within neural circuits. BigNeuron is a new community effort that combines modern bioimaging informatics, recent leaps in labeling and microscopy, and the widely recognized need for openness and standardization to provide a community resource for automated reconstruction of dendritic and axonal morphology of single neurons.

MeSH terms

  • Algorithms
  • Animals
  • Computational Biology
  • Humans
  • Imaging, Three-Dimensional*
  • Microscopy / methods*
  • Models, Neurological*
  • Neurons / cytology*
  • Optical Imaging