[Antiviral activity of aqueous extracts of the birch fungus Inonotus obliquus on the human immunodeficiency virus]

Vopr Virusol. 2015;60(2):35-8.
[Article in Russian]


Fractions of aqueous and water-alcohol extracts of the birch fungus Inonotus obliquus have antiviral effect against the human immunodeficiency virus type 1 (HIV-1). Antiviral properties of low toxic extracts were manifested in the concentration of 5.0 μg/ml upon simultaneous application with the virus in the lymphoblastoid cells culture MT-4. The extract of the birch fungus can be used for development of new antiviral drugs, inhibitors of HIV-replication when used both in the form of individual drugs and as a part of complex therapy.

Publication types

  • English Abstract

MeSH terms

  • Anti-HIV Agents / chemistry
  • Anti-HIV Agents / pharmacology*
  • Basidiomycota / chemistry*
  • Cell Line, Tumor
  • Complex Mixtures / chemistry
  • Complex Mixtures / pharmacology*
  • Ethanol / chemistry
  • HIV Infections / drug therapy*
  • HIV Infections / metabolism
  • HIV Infections / pathology
  • HIV-1 / physiology*
  • Humans
  • Virus Replication / drug effects*
  • Water / chemistry


  • Anti-HIV Agents
  • Complex Mixtures
  • Water
  • Ethanol