Towards host-directed therapies for tuberculosis

Nat Rev Drug Discov. 2015 Aug;14(8):511-2. doi: 10.1038/nrd4696. Epub 2015 Jul 17.


The treatment of tuberculosis is based on combinations of drugs that directly target Mycobacterium tuberculosis. A new global initiative is now focusing on a complementary approach of developing adjunct host-directed therapies.

MeSH terms

  • Antitubercular Agents / administration & dosage
  • Antitubercular Agents / pharmacology
  • Antitubercular Agents / therapeutic use*
  • Drug Design*
  • Drug Therapy, Combination
  • Humans
  • Molecular Targeted Therapy
  • Mycobacterium tuberculosis / drug effects
  • Tuberculosis / drug therapy*


  • Antitubercular Agents