Optimizing Enrollment of Patients into Nephrology Research Studies

Clin J Am Soc Nephrol. 2016 Mar 7;11(3):512-7. doi: 10.2215/CJN.00500115. Epub 2015 Jul 16.


Advances in medical care and biomedical research depend on the participation of human subjects. Poor patient enrollment in research has limited past clinical and translational research endeavors in nephrology. Simultaneously, patients and their caregivers are seeking better diagnostic, monitoring, and therapeutic approaches to improve or restore kidney and overall health. This manuscript will discuss a framework and strategies to optimize patient enrollment within nephrology research and provide examples of success from existing nephrology research programs.

Keywords: CKD; clinical trial; patient engagement; recruitment; study participation.

MeSH terms

  • Attitude of Health Personnel
  • Biomedical Research / methods*
  • Community-Institutional Relations
  • Delivery of Health Care
  • Health Knowledge, Attitudes, Practice
  • Humans
  • Nephrology / methods*
  • Patient Acceptance of Health Care
  • Patient Selection*
  • Research Subjects* / psychology
  • Sample Size