Remodeling Your Way out of Cell Cycle

Erdem Sendinc; Ashwini Jambhekar; Yang Shi

doi:10.1016/j.cell.2015.06.050

Remodeling Your Way out of Cell Cycle

Cell. 2015 Jul 16;162(2):237-238. doi: 10.1016/j.cell.2015.06.050.

Authors

Erdem Sendinc¹, Ashwini Jambhekar¹, Yang Shi²

Affiliations

¹ Division of Newborn Medicine, Children's Hospital Boston, 300 Longwood Avenue, Boston, MA 02115, USA; Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA.
² Division of Newborn Medicine, Children's Hospital Boston, 300 Longwood Avenue, Boston, MA 02115, USA; Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA. Electronic address: yang_shi@hms.harvard.edu.

PMID: 26186182
DOI: 10.1016/j.cell.2015.06.050

Abstract

Throughout development, proliferative progenitors lose their mitotic potential, exit the cell cycle, and differentiate. In this issue, Ruijtenberg and van den Heuvel identify an important lineage-specific role for a SWI/SNF chromatin-remodeling complex that collaborates with core cell-cycle regulators to promote cell-cycle exit and terminal muscle cell differentiation.

Publication types

Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Comment

MeSH terms

Animals
Caenorhabditis elegans / cytology*
Caenorhabditis elegans / growth & development*
Muscles / cytology*

Abstract

Publication types

MeSH terms

Grants and funding