Motion of nanoprobes in complex liquids within the framework of the length-scale dependent viscosity model

Adv Colloid Interface Sci. 2015 Sep;223:55-63. doi: 10.1016/j.cis.2015.06.007. Epub 2015 Jul 10.


This paper deals with the recent phenomenological model of the motion of nanoscopic objects (colloidal particles, proteins, nanoparticles, molecules) in complex liquids. We analysed motion in polymer, micellar, colloidal and protein solutions and the cytoplasm of living cells using the length-scale dependent viscosity model. Viscosity monotonically approaches macroscopic viscosity as the size of the object increases and thus gives a single, coherent picture of motion at the nano and macro scale. The model includes interparticle interactions (solvent-solute), temperature and the internal structure of a complex liquid. The depletion layer ubiquitously occurring in complex liquids is also incorporated into the model. We also discuss the biological aspects of crowding in terms of the length-scale dependent viscosity model.

Keywords: Complex liquids; Diffusion; Length-scale dependence; Soft matter; Viscosity.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Colloids / chemistry
  • Diffusion
  • Models, Chemical*
  • Nanoparticles / chemistry*
  • Proteins / chemistry
  • Solutions / chemistry
  • Solvents
  • Temperature
  • Viscosity


  • Colloids
  • Proteins
  • Solutions
  • Solvents