Biomacromolecular logic gate, encoder/decoder and keypad lock based on DNA damage with electrochemiluminescence and electrochemical signals as outputs

Chem Commun (Camb). 2015 Aug 28;51(67):13185-8. doi: 10.1039/c5cc04412j.


Based on the damage of natural DNA, a 3-input/4-output logic gate system and other biomacromolecular devices, such as a 2-to-1 encoder, a 1-to-2 decoder and a keypad lock, were developed using simultaneously obtained electrochemiluminescence (ECL) and cyclic voltammetry (CV) signals as outputs in the presence of Ru(bpy)3(2+).

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • 2,2'-Dipyridyl / analogs & derivatives
  • 2,2'-Dipyridyl / chemistry
  • Coordination Complexes
  • DNA Damage*
  • Electrochemical Techniques
  • Luminescent Measurements / instrumentation
  • Models, Biological


  • Coordination Complexes
  • tris(2,2-bipyridine)-ruthenium(II)
  • 2,2'-Dipyridyl