Contrast Medium-Induced Acute Kidney Injury

Cardiorenal Med. 2015 Jun;5(3):219-28. doi: 10.1159/000430770.


Contrast medium-induced acute kidney injury (CI-AKI) is a predominant cause of hospital-acquired renal insufficiency. With an increasing number of contrast medium-enhanced radiological procedures being performed in a rapidly increasing ageing population in the Western world, it is imperative that more attention is given to understand the aetiology of CI-AKI to devise novel diagnostic methods and to formulate effective prophylactic and therapeutic regimens to reduce its incidence and its associated morbidity and mortality. This article presents high-yield information on the above-mentioned aspects of CI-AKI, primarily based on results of randomised controlled trials, meta-analyses, systematic reviews and international consensus guidelines.

Keywords: Acute kidney injury; Ascorbic acid; Contrast medium; N-acetylcysteine; Neutrophil gelatinase-associated lipocalcin; RenalGuard™ system; Risk prediction; Serum creatinine; Statins.

Publication types

  • Review