Selected Micronutrients in Cognitive Decline Prevention and Therapy

Mol Neurobiol. 2016 Aug;53(6):4083-4093. doi: 10.1007/s12035-015-9349-1. Epub 2015 Jul 22.

Abstract

Population aging is a worldwide demographic trend. Consequently, the prevalence of chronic age-related conditions such as clinically diagnosed neurological diseases, cognitive decline, and dementia will significantly increase in the near future. The important role of diets and healthy lifestyle as preventative of neurodegenerative diseases is widely accepted nowadays, and it may provide preventive strategies in very early, non-symptomatic phases of dementia well, especially because there are still no effective treatments for it. In this article, we review the known effects of selected micronutrients on the aging brain and we propose strategies for dietary improvements.

Keywords: Alzheimer’s; Cognitive decline; Micronutrients; Polyphenols; Vitamins.

Publication types

  • Review
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alzheimer Disease / prevention & control
  • Alzheimer Disease / therapy
  • Cognitive Dysfunction / prevention & control*
  • Cognitive Dysfunction / therapy*
  • Humans
  • Micronutrients / therapeutic use*

Substances

  • Micronutrients