Surgical treatment is effective in severe cases of exercise-induced laryngeal obstruction: A follow-up study

Acta Otolaryngol. 2015;135(11):1152-9. doi: 10.3109/00016489.2015.1062548. Epub 2015 Jul 22.


Conclusions: Surgery is an effective treatment in severe cases of supraglottic exercise-induced laryngeal obstruction (E-ILO). Conservatively treated subjects and subjects tested negative for E-ILO, who still experience breathing problems 1-3 years after diagnosis, tend to adjust their physical activity to a greater extent than surgically treated subjects.

Objective: To investigate how symptoms and level of physical activity change over time in patients with E-ILO who have undergone surgery, patients with E-ILO treated conservatively and patients who tested negative for laryngeal obstruction at continuous laryngoscopy exercise-test (CLE-test).

Methods: Patients referred for exercise-induced breathing difficulties answered questionnaires at diagnostic CLE-test and at follow-up. Questions regarded exercise-induced breathing problems, current physical activity level, and medical history of asthma and perennial allergy.

Results: Out of 84 invited subjects, 59 (70%) answered both questionnaires. Surgically treated subjects had less breathing problems at follow-up compared with conservatively treated subjects and subjects who tested negative (p < 0.001). None of the surgically treated subjects were less physically active or had changed sport due to exercise-induced dyspnoea, whereas 41.7% of the conservatively treated subjects had made such adjustments (p < 0.001).

Keywords: E-ILO; Laryngoplasty; exercice-induced dyspnoea; physical activity; vocal cord dysfunction.

Publication types

  • Observational Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Exercise Test / adverse effects*
  • Female
  • Follow-Up Studies
  • Humans
  • Laryngoplasty / methods*
  • Laryngoscopy
  • Laryngostenosis / diagnosis
  • Laryngostenosis / etiology
  • Laryngostenosis / surgery*
  • Male
  • Time Factors
  • Treatment Outcome
  • Young Adult