Electrochemical analysis of a novel ferrocene derivative as a potential antitumor drug

Analyst. 2015 Sep 7;140(17):5864-7. doi: 10.1039/c5an00958h.


Ferrocenes represent an interesting group of drugs with potential antitumor properties. Moreover, their electronic properties make them suitable for electrochemical studies. We determined an uptake of a novel ferrocene derivative in low μM concentrations by selected cancer cell lines and showed its localization predominantly in cytoplasm, using glassy carbon electrodes.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antineoplastic Agents / analysis*
  • Antineoplastic Agents / pharmacology
  • Cell Line, Tumor
  • Cell Survival / drug effects
  • Electrochemical Techniques*
  • Electrodes
  • Ferrous Compounds / chemistry*
  • Ferrous Compounds / pharmacology
  • Humans
  • MCF-7 Cells
  • Metallocenes
  • Reactive Oxygen Species / chemistry


  • Antineoplastic Agents
  • Ferrous Compounds
  • Metallocenes
  • Reactive Oxygen Species
  • ferrocene