Prevention of Postoperative Cerebrospinal Fluid Leaks After Translabyrinthine Tumor Resection With Resorbable Mesh Cranioplasty

Otol Neurotol. 2015 Sep;36(9):1537-42. doi: 10.1097/MAO.0000000000000835.


Objectives: To evaluate the effectiveness of resorbable mesh cranioplasty at reducing postoperative cerebrospinal fluid (CSF) leak and pseudomeningocele formation after translabyrinthine tumor resection.

Study design: Case series with chart review.

Setting: Tertiary academic referral center.

Patients: Fifty-three consecutive cases using a resorbable mesh cranioplasty after translabyrinthine tumor resection were reviewed.

Intervention: Temporal bone defects were repaired with a dural substitute, layered fat graft, and a resorbable mesh plate secured with screws.

Main outcome measures: Primary outcome measures included the incidence of postoperative CSF wound leak or rhinorrhea, pseudomeningocele formation, and surgical site infection.

Results: Fifty-three cases (average age, 54.0 yr; range, 19.3-75.1 yr) were analyzed. The average body mass index was 30.8 kg/m2 (range, 17.9-48.3 kg/m2), and the average tumor size was 18.8 mm (range, 8-38 mm). One patient (1.9%) experienced CSF rhinorrhea on postoperative Day 16, which resolved after transmastoid middle ear and eustachian tube packing. One patient (1.9%) experienced a surgical site infection requiring surgical debridement and mesh removal 4 months after surgery. Compared with 1,441 prior translabyrinthine surgeries analyzed from our institution using a traditional fat graft closure without mesh, the rate of postoperative CSF leak was significantly less using the resorbable mesh cranioplasty technique (p = 0.0483).

Conclusion: Resorbable mesh cranioplasty is a safe and effective method to reduce postoperative CSF leak and pseudomeningocele formation after translabyrinthine craniotomy for tumor excision.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Bone Plates
  • Cerebrospinal Fluid Otorrhea / prevention & control*
  • Cerebrospinal Fluid Rhinorrhea / prevention & control*
  • Craniotomy / methods*
  • Eustachian Tube / surgery
  • Female
  • Humans
  • Male
  • Meningocele
  • Middle Aged
  • Neuroma, Acoustic / surgery*
  • Postoperative Complications / prevention & control*
  • Retrospective Studies
  • Surgical Mesh*
  • Temporal Bone / surgery*
  • Young Adult