One shot of carbon-ion radiotherapy cured a 6-cm chemo-resistant metastatic liver tumor: a case of breast cancer

Jpn J Radiol. 2015 Sep;33(9):598-602. doi: 10.1007/s11604-015-0462-x. Epub 2015 Jul 29.


The standard treatment for metastatic liver tumor from breast cancer is systemic medical treatment, and there is controversy regarding the value of local treatment. However, there are some exceptional cases that do benefit from local therapy. We describe the case of a 54-year-old woman with systemic therapy-resistant liver metastasis from breast cancer successfully treated with a single shot of 36-GyE carbon-ion radiotherapy and surviving more than 8 years without local recurrence. This case represents a good example of the usefulness and safety of carbon-ion radiotherapy, and who might benefit from local therapy.

Keywords: Breast cancer; Carbon-ion radiotherapy; Metastatic liver tumor.

Publication types

  • Case Reports

MeSH terms

  • Breast Neoplasms / pathology*
  • Female
  • Heavy Ion Radiotherapy*
  • Humans
  • Liver Neoplasms / drug therapy
  • Liver Neoplasms / radiotherapy*
  • Liver Neoplasms / secondary*
  • Middle Aged
  • Neoplasms, Second Primary / drug therapy
  • Neoplasms, Second Primary / radiotherapy*
  • Neoplasms, Second Primary / secondary
  • Treatment Outcome