Objective: An evaluation of the effect of chlorhexidine/ketoconazole shampoo baths on the flea control efficacy of indoxacarb applied topically to dogs.
Methods and results: We randomly allocated 18 healthy mixed-breed dogs to 3 groups: shampoo only; indoxacarb treated and medicated shampoo; and indoxacarb treated but not shampooed. Indoxacarb was administered on day 0 and dogs were shampooed on days 9 and 23. Dogs were infested with 100 adult Ctenocephalides felis initially 2 days before treatment and then weekly from days 7 to 28. Fleas were removed and counted 48 h post-infestation.
Conclusion: Medicated shampoo use did not significantly reduce indoxacarb efficacy against C. felis.
Keywords: chlorhexidine; dogs; fleas; indoxacarb; ketoconazole; shampoo.
© 2015 MSD Animal Health. Australian Veterinary Journal published by Wiley Publishing Asia Pty Ltd on behalf of Australian Veterinary Association.