Six month follow-up of fourteen victims with short-term exposure to chlorine gas

J Soc Occup Med. 1989 Winter;39(4):131-2. doi: 10.1093/occmed/39.4.131.


Fourteen cases, 5 with pre-existing COAD, exposed to up to 30 p.p.m. chlorine gas in an accidental leakage, were followed up clinically, radiologically and by spirometry at 2 weeks, 4 weeks, 8 weeks and 6 months. All the patients were asymptomatic by 2 weeks and did not reveal any radiological abnormality. The FVC, FEV1 and FVC observed/predicted improved at 4 weeks (p less than 0.05, p less than 0.05, p less than 0.01) and the improvement in FEF0.25-0.75 reached statistical significance (p less than 0.05) at 6 months. The mean improvement in FVC was 0.84 l and FEV1 was 0.6 l at 4 weeks. The 5 patients with pre-existing COAD did not show any evidence of additional lung damage. The observations have been consistent with acute tracheobronchitis with trends towards complete recovery.

MeSH terms

  • Adult
  • Chlorine / poisoning*
  • Follow-Up Studies
  • Gas Poisoning / diagnosis*
  • Humans
  • India
  • Lung Diseases, Obstructive / diagnosis
  • Male
  • Middle Aged
  • Occupational Diseases / diagnosis*
  • Spirometry
  • Time Factors


  • Chlorine